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Peptide Cycles and Dosage Guidelines
Comprehensive guidelines for peptide cycling protocols and dosage recommendations across different peptide categories for bodybuilders.
Introduction
Proper cycling and dosage protocols are essential for maximizing peptide benefits while minimizing risks. This guide provides structured recommendations for various peptide categories.
GH Secretagogue Cycling
Standard GH Stack Protocol
| Phase | Duration | CJC-1295 | Ipamorelin | Timing |
|---|---|---|---|---|
| Loading | Weeks 1-2 | 100mcg 2x/day | 200mcg 2x/day | AM + Pre-bed |
| Maintenance | Weeks 3-12 | 100mcg 2x/day | 200mcg 2x/day | AM + Pre-bed |
| Taper | Weeks 13-14 | 50mcg 2x/day | 100mcg 2x/day | AM + Pre-bed |
| Off-cycle | 4-6 weeks | None | None | - |
Single Peptide Protocols
| Peptide | Starting Dose | Max Dose | Frequency |
|---|---|---|---|
| Ipamorelin | 100mcg | 300mcg | 2-3x daily |
| GHRP-2 | 50mcg | 150mcg | 2-3x daily |
| GHRP-6 | 50mcg | 150mcg | 2-3x daily |
| Sermorelin | 200mcg | 500mcg | 1-2x daily |
Recovery Peptide Protocols
BPC-157 Guidelines
| Application | Dose | Route | Duration |
|---|---|---|---|
| Acute injury | 250-500mcg/day | Local injection | 4-8 weeks |
| Chronic issues | 200-300mcg/day | Systemic | 8-12 weeks |
| Prevention | 100-200mcg/day | Systemic | 2-4 weeks periodically |
TB-500 Guidelines
| Phase | Dose | Frequency | Duration |
|---|---|---|---|
| Loading | 5-10mg/week | 2x weekly | 4-6 weeks |
| Maintenance | 2-5mg/week | 1-2x weekly | As needed |
| Prevention | 2mg/week | Weekly | Ongoing |
Dosage Adjustment Factors
Individual Variables
| Factor | Adjustment | Rationale |
|---|---|---|
| Body weight | ±20% for significant differences | Larger individuals may need more |
| Age | Often lower for >40 | Increased sensitivity |
| Response | Titrate based on effects | Individual variation |
| Goals | Match to objectives | Fat loss vs. recovery |
Timing Considerations
| Peptide Type | Optimal Timing | Notes |
|---|---|---|
| GH secretagogues | Fasted, AM + pre-bed | Maximize GH pulse |
| Recovery | Morning + before bed | Healing during sleep |
| Fat loss | AM fasted | Enhanced lipolysis |
Cycling Strategies
Receptor Sensitivity Management
| Approach | On-Cycle | Off-Cycle | Purpose |
|---|---|---|---|
| Standard | 12 weeks | 4 weeks | Maintain sensitivity |
| Conservative | 8 weeks | 4 weeks | Minimize adaptation |
| Extended | 16 weeks | 6-8 weeks | Experienced users |
Conclusion
Following structured cycling and dosage protocols optimizes results while supporting health. Individual adjustment based on response is key to long-term success.
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References
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